Leukodystrophy and myelin / Hugo Moser and Gerald Raymond -- Myelination in health and disease / Graham Kidd and Bruce D. Trapp -- The role of astrocytes in white-matter disease / Jorg Dietrich and Chris Proschel -- Microglia and leukodystrophies / Patricia Musolino and Florian Eichler -- X-linked adrenoleukodystrophy / Gerald V. Raymond -- Krabbe disease (globoid cell leukodystrophy) / David A. Wenger -- Alexander disease / Daniel Flint and Michael Brenner -- Metachromatic leukodystrophy / Volkmar Gieselman and Ingeborg Krageloh-Mann -- Canavan disease / Kimberlee Michals and Reuben Matalon -- Pelizaeus Merzbacher disease : genetic models and mechanisms / Klaus-Armin Nave and Ajit Singh Dhaunchak -- Therapeutic approaches in leukodystrophies /Ali Fatemi and Charles Peters -- Clinical approach to identification of leukoencephalopathies / Sakkubai Naidu, Genila Bibat and Doris Lin.