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Title Chimeric antigen receptor T-cell therapies for cancer [electronic resource] : a practical guide / edited by Daniel W. Lee, Nirali N. Shah.
Published/Produced Amsterdam, Netherlands : Elsevier, [2020].
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ISBN 9780323755979
0323755976
9780323661812
0323661815
Physical description 1 online resource (xi, 222 pages) : illustrations(chiefly color).
Notes Includes bibliographical references.
Contents Introduction -- When to refer a patient for CAR-T cell therapy -- Optimizing the apheresis product -- CAR T cells: cell processing laboratory considerations -- Peri-CAR-T cell management -- Management of cytokine release syndrome -- Special considerations for ICU management of patients receiving CAR therapy -- Neurotoxicities after CAR-T cell immunotherapy -- Hematologic and non-CRS toxicities -- Response assessment and post-CAR-T cell therapy management -- Relapse management and role for consolidative hematopoietic stem cell transplantation following CAR-T cell therapy -- Promising chimeric antigen receptors for non-B cell hematological malignancies, pediatric solid tumors, and carcinomas -- CAR T cell therapy for CNS malignancies -- CAR 2.0: the next generation of synthetic receptor-based cellular therapy for cancer.
Subjects T cells -- Receptors.
Tumor antigens.
Receptors, Chimeric Antigen -- therapeutic use.
Neoplasms -- therapy.
Immunotherapy, Adoptive.
Receptors, Antigen, T-Cell.
Cell- and Tissue-Based Therapy.
Related names Lee, Daniel W., editor.
Shah, Nirali, MD, editor.