Background and history -- Basic cell biology : structure and function of genes and chromosomes -- Genetic variation : its origin and detection -- Autosomal dominant and recessive inheritance -- Sex-linked and non-traditional modes of inheritance -- Clinical cytogenetics : the chromosomal basis of human disease -- Biochemical genetics : disorders of metabolism -- Disease-gene identification -- Immunogenetics -- Genetic basis of development -- Cancer genetics -- Multifactorial inheritance and common diseases -- Genetic testing and gene therapy -- Genetics and precision medicine -- Clinical genetics and genetic counselling.